Some Esters of Palmitic Acid

Xlii. Some Esters of Palmitic Acid

Metabolism of L-Carnitine Esters of ,&&ibstituted Palmitic Acid by Rat Liver Mitochondria*

The chemical synthesis and properties of L-carnitine esters of P-ketopalmitic acid, /3-hydroxypslmitic acid, and ~ranstr,P-unsaturated palmitic acid are described. Isolated rat liver mitochondria oxidize the carnitine esters of these acids more efficiently than the free acids as judged by acetoacetate production and oxygen uptake. Rat liver mitochondrial extracts catalyze the conversion of palm...

Evaluation of linoleic acid, eladic acid and palmitic acid for cytotoxicity and anti-inflammatory activities

Background and objectives: Nigella sativa seeds have shown to possess anti-inflammatory, anti-oxidant, trenquillizer, chemopreventive and anti-neoplastic effects. Besides, they areused as nutritional flavoring agents. We have investigated the protective effects of N.  sativa seeds hexane extract and active principles against methyl phenyl pyridine (MP...

Protective Effects of Linoleic Acid against the Cytotoxicity of Palmitic Fatty Acid in Rat Cardiomyocytes

Background & Aims: Lipotoxicity is the process through which accumulation of lipid intermadiates leads to cellular dysfunction. The worldwide prevalence of cardiovascular diseases has been increased dramatically due to lipotoxicity. According to the peformed studies, saturated and unsaturated fatty acids differ significantly in their contributions to lipotoxicity. It has been r...

Utilization of palmitic acid by Mycobacterium avium.

Mycobacterium avium accumulates (14)C-palmitic acid with saturation kinetics; the process is both temperature dependent and pH sensitive. The fatty acid is incorporated into triglyceride in vivo and the conversion is detectable within 5 min after exposure of the cells to (14)C-palmitic acid. The triglyceride is rapidly utilized because (14)CO(2) evolution from it begins within 30 min after (14)...